Download PDF by Donglu Zhang,Sekhar Surapaneni: ADME-Enabling Technologies in Drug Design and Development

By Donglu Zhang,Sekhar Surapaneni

A accomplished consultant to state of the art instruments in ADME research

The final decade has obvious super development within the improvement of analytical innovations resembling mass spectrometry and molecular biology instruments, leading to very important advances in drug discovery, relatively within the zone of absorption, distribution, metabolism, and excretion (ADME).

ADME-Enabling applied sciences in Drug layout and improvement makes a speciality of the present cutting-edge within the box, proposing a finished overview of the newest instruments for producing ADME info in drug discovery. It examines the broadest attainable variety of obtainable applied sciences, giving readers the knowledge they should opt for definitely the right software for a given software, a key needful for acquiring favorable leads to a well timed style for regulatory filings. With over thirty contributed chapters by means of a global crew of specialists, the publication provides:

  • A thorough exam of present instruments, overlaying either electronic/mechanical applied sciences and biologically dependent ones

  • Coverage of functions for every know-how, together with key parameters, optimum stipulations for meant effects, protocols, and case studies

  • Detailed dialogue of rising instruments and methods, from stem cells and genetically converted animal versions to imaging technologies

  • Numerous figures and diagrams during the text

Scientists and researchers in drug metabolism, pharmacology, medicinal chemistry, pharmaceutics, toxicology, and bioanalytical technological know-how will locate ADME-Enabling applied sciences in Drug layout and improvement a useful consultant to the whole drug improvement approach, from discovery to regulatory issues.

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ADME-Enabling Technologies in Drug Design and Development by Donglu Zhang,Sekhar Surapaneni


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